Methyl 2,3-dihydro-1H-indole-5-carboxylate - Names and Identifiers
Name | methyl indoline-5-carboxylate
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Synonyms | methyl indoline-5-carboxylate Methyl indoline-5-carboxylate methyl 2,3-dihydro-1H-indole-5-carboxylate Methyl 2,3-dihydro-1H-indole-5-carboxylate 2,3-Dihydro-1H-indol-5-carboxylic acid methyl ester 1H-Indole-5-carboxylicacid, 2,3-dihydro-, methyl ester 1H-indole-5-carboxylic acid, 2,3-dihydro-, methyl ester
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CAS | 141452-01-9
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InChI | InChI=1/C10H11NO2/c1-13-10(12)8-2-3-9-7(6-8)4-5-11-9/h2-3,6,11H,4-5H2,1H3 |
Methyl 2,3-dihydro-1H-indole-5-carboxylate - Physico-chemical Properties
Molecular Formula | C10H11NO2
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Molar Mass | 177.2 |
Density | 1.162±0.06 g/cm3(Predicted) |
Melting Point | 67-69 °C |
Boling Point | 331.0±31.0 °C(Predicted) |
Flash Point | 153.956°C |
Solubility | DMSO (Sparingly), Methanol (Slightly) |
Vapor Presure | 0mmHg at 25°C |
Appearance | Solid |
Color | Off-White |
pKa | 2.65±0.20(Predicted) |
Storage Condition | Keep in dark place,Sealed in dry,2-8°C |
Refractive Index | 1.555 |
Methyl 2,3-dihydro-1H-indole-5-carboxylate - Introduction
Indoline-5-carboxylic acid methyl ester, also known as indoline-5-carboxylic acid methyl ester, is an organic compound. The following is an introduction to the properties, uses, preparation methods and safety information of indoline -5-carboxylic acid methyl ester:
Nature:
-Appearance: Indoline -5-methyl formate is a colorless liquid.
-Molecular formula: C12H9NO2
-Molecular weight: 199.21g/mol
-Melting point: No definite melting point data.
-Boiling point: about 250°C (exact boiling point data may vary).
-Solubility: Soluble in organic solvents such as ethanol and dichloromethane, insoluble in water.
Use:
Indoline -5-carboxylic acid methyl ester has many uses in organic synthesis, such:
-As an intermediate in organic synthesis, it can be used to synthesize indoline derivatives and other organic compounds.
-In the pharmaceutical field, it can be used to synthesize anti-cancer drugs, etc.
-It can be used as an intermediate for electronic materials, such as organic light-emitting diodes (OLED).
-For chemical research and organic synthesis reactions in the laboratory.
Preparation Method:
Indoline-5-carboxylic acid methyl ester is usually prepared by the following steps:
1. First, indoline -5-formic acid is reacted with formic anhydride under acidic conditions to generate indoline -5-carboxylic acid methyl ester.
2. After the reaction is completed, the desired product is purified by distillation or other methods.
Safety Information:
As an organic compound, indoline-5-carboxylic acid methyl ester has certain safety risks. Here is the relevant safety information:
-May be irritating to eyes and skin, be careful when touching.
-Avoid contact with strong oxidants during use or storage.
-Wear appropriate personal protective equipment such as goggles, gloves and lab coats when handling or handling.
-should be used in well-ventilated conditions, avoid inhalation of vapor or dust.
-If ingested or inhaled, seek medical help immediately and provide information about the chemical.
It should be noted that for the use and operation of chemicals, please strictly follow the relevant safety operation procedures and use them under the guidance of professionals.
Last Update:2024-04-09 21:01:54